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TH-PVP

Chemical compound From Wikipedia, the free encyclopedia

TH-PVP
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TH-PVP is a substituted cathinone derivative which has been sold as a designer drug. It was first identified by a forensic laboratory in Hungary in 2015,[2] but has subsequently been found in numerous other countries around the world including Spain, Belgium, Poland, Turkey and Brazil.[3][4][5][6][7][8]

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Pharmacological studies in vitro showed it to inhibit reuptake of the monoamine neurotransmitters, with about 10-fold selectivity for serotonin over norepinephrine and dopamine, whereas the drug did not induce monoamine release.[9] Despite its activity as a monoamine reuptake inhibitor, TH-PVP failed to produce stimulant effects in animals.[10]

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