THRAP3

Thyroid hormone receptor-associated protein 3 is a protein that in humans is encoded by the THRAP3 gene.^[5]

THRAP3
Identifiers
Aliases	THRAP3, TRAP150, thyroid hormone receptor associated protein 3, BCLAF2
External IDs	OMIM: 603809; MGI: 2442637; HomoloGene: 31289; GeneCards: THRAP3; OMA:THRAP3 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p34.3 Start 36,224,416 bp[1] End 36,305,357 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D2.2 Start 126,164,082 bp[2] End 126,202,760 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle ventricular zone Achilles tendon ganglionic eminence stromal cell of endometrium muscle of thigh Descending thoracic aorta gastric mucosa right coronary artery right lobe of thyroid gland Top expressed in tail of embryo genital tubercle ventricular zone neural layer of retina spermatocyte yolk sac epiblast lip Rostral migratory stream muscle of thigh More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding transcription coactivator activity transcription coregulator activity thyroid hormone receptor binding phosphoprotein binding core promoter sequence-specific DNA binding protein binding nuclear receptor coactivator activity ATP binding vitamin D receptor binding RNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity Cellular component nuclear speck mediator complex exon-exon junction complex nucleoplasm extracellular exosome nucleus Biological process androgen receptor signaling pathway regulation of transcription, DNA-templated positive regulation of mRNA splicing, via spliceosome rhythmic process mRNA processing intracellular steroid hormone receptor signaling pathway regulation of alternative mRNA splicing, via spliceosome transcription, DNA-templated positive regulation of transcription, DNA-templated nuclear-transcribed mRNA catabolic process mRNA stabilization circadian rhythm RNA splicing positive regulation of circadian rhythm transcription initiation from RNA polymerase II promoter positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9967 230753 Ensembl ENSG00000054118 ENSMUSG00000043962 UniProt Q9Y2W1 Q569Z6 RefSeq (mRNA) NM_005119 NM_001321471 NM_001321473 NM_146153 NM_001356455 NM_001356456 RefSeq (protein) NP_001308400 NP_001308402 NP_005110 NP_666265 NP_001343384 NP_001343385 Location (UCSC) Chr 1: 36.22 – 36.31 Mb Chr 4: 126.16 – 126.2 Mb PubMed search [3] [4]
Wikidata
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