TIMM9

Mitochondrial import inner membrane translocase subunit Tim9 is an enzyme that in humans is encoded by the TIMM9 gene.^[5][6][7]

TIMM9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2BSK
Identifiers
Aliases	TIMM9, TIM9, TIM9A, translocase of inner mitochondrial membrane 9
External IDs	OMIM: 607384; MGI: 1353436; HomoloGene: 40847; GeneCards: TIMM9; OMA:TIMM9 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q23.1 Start 58,408,495 bp[1] End 58,427,531 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12 C2|12 Start 71,169,947 bp[2] End 71,183,458 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas ganglionic eminence muscle of thigh epithelium of colon ventricular zone gastrocnemius muscle left ovary gonad muscle layer of sigmoid colon right ovary Top expressed in primary oocyte right kidney embryo secondary oocyte embryo blastocyst proximal tubule yolk sac dentate gyrus of hippocampal formation granule cell superior frontal gyrus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding chaperone binding protein binding protein homodimerization activity metal ion binding transporter activity Cellular component mitochondrial inner membrane mitochondrial intermembrane space mitochondrial intermembrane space protein transporter complex membrane mitochondrion TIM22 mitochondrial import inner membrane insertion complex Biological process protein transport protein insertion into mitochondrial inner membrane protein targeting to mitochondrion hearing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26520 30056 Ensembl ENSG00000100575 ENSMUSG00000021079 UniProt Q9Y5J7 Q9WV98 RefSeq (mRNA) NM_001304485 NM_001304486 NM_001304487 NM_001304488 NM_001304489 NM_001304490 NM_001304491 NM_012460 NM_001024853 NM_001024854 NM_001286203 NM_013896 RefSeq (protein) NP_001291414 NP_001291415 NP_001291416 NP_001291417 NP_001291418 NP_001291419 NP_001291420 NP_036592 NP_001020024 NP_001020025 NP_001273132 NP_038924 Location (UCSC) Chr 14: 58.41 – 58.43 Mb Chr 12: 71.17 – 71.18 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

TIMM9 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space.

These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM]^[7]