TINAG

Tubulointerstitial nephritis antigen is a protein that in humans is encoded by the TINAG gene.^[5][6]

TINAG
Identifiers
Aliases	TINAG, TIN-AG, tubulointerstitial nephritis antigen
External IDs	OMIM: 606749; MGI: 1349477; HomoloGene: 8082; GeneCards: TINAG; OMA:TINAG - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p12.1 Start 54,307,859 bp[1] End 54,390,142 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 D Start 76,858,975 bp[2] End 76,953,076 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of ileum human kidney rectum mucosa of transverse colon jejunal mucosa mucosa of sigmoid colon testicle duodenum renal cortex gallbladder Top expressed in human kidney right kidney Paneth cell left lung lobe efferent ductule left colon ileum intestinal villus jejunum duodenum More reference expression data BioGPS n/a
Gene ontology Molecular function scavenger receptor activity nucleotide binding cysteine-type endopeptidase activity polysaccharide binding cysteine-type peptidase activity Cellular component basement membrane extracellular region lysosome extracellular space Biological process cell adhesion proteolysis involved in cellular protein catabolic process receptor-mediated endocytosis immune response proteolysis vesicle-mediated transport endocytosis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27283 26944 Ensembl ENSG00000137251 ENSMUSG00000032357 UniProt Q9UJW2 n/a RefSeq (mRNA) NM_014464 NM_012033 RefSeq (protein) NP_055279 n/a Location (UCSC) Chr 6: 54.31 – 54.39 Mb Chr 9: 76.86 – 76.95 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

TINAG is a basement membrane glycoprotein initially identified as a target of antibodies in some forms of immunologically mediated tubulointerstitial nephritis.[supplied by OMIM]^[6]