TMEPAI

Transmembrane prostate androgen-induced protein is a protein that in humans is encoded by the PMEPA1 gene.^[5][6]

PMEPA1
Identifiers
Aliases	PMEPA1, STAG1, TMEPAI, prostate transmembrane protein, androgen induced 1
External IDs	OMIM: 606564; MGI: 1929600; HomoloGene: 10608; GeneCards: PMEPA1; OMA:PMEPA1 - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q13.31 Start 57,648,392 bp[1] End 57,711,536 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 H3 Start 173,066,251 bp[2] End 173,118,326 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in visceral pleura ascending aorta Descending thoracic aorta popliteal artery tibial arteries tibia tendon of biceps brachii canal of the cervix urethra prostate Top expressed in ascending aorta aortic valve external carotid artery internal carotid artery tunica media of zone of aorta brown adipose tissue subcutaneous adipose tissue interventricular septum white adipose tissue sciatic nerve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function WW domain binding R-SMAD binding protein binding Cellular component integral component of membrane Golgi membrane endosome plasma membrane Golgi apparatus early endosome membrane endosome membrane intracellular membrane-bounded organelle membrane Biological process androgen receptor signaling pathway negative regulation of signal transduction negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of pathway-restricted SMAD protein phosphorylation negative regulation of SMAD protein complex assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56937 65112 Ensembl ENSG00000124225 ENSMUSG00000038400 UniProt Q969W9 Q9D7R2 RefSeq (mRNA) NM_199171 NM_001255976 NM_020182 NM_199169 NM_199170 NM_022995 RefSeq (protein) NP_001242905 NP_064567 NP_954638 NP_954639 NP_954640 n/a Location (UCSC) Chr 20: 57.65 – 57.71 Mb Chr 2: 173.07 – 173.12 Mb PubMed search [3] [4]
Wikidata
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Interactions

TMEPAI has been shown to interact with NEDD4.^[7]