TMIGD1

Transmembrane and immunoglobulin domain containing 1 is a protein that in humans is encoded by the TMIGD1 gene.^[5] TMIGD1 was discovered by the lab of Giancarlo Marra^[6] and later cloned by Nader Rahimi.^[7][8] Recent findings suggest functions in brush border formation (intestinal epithelium) and roles as tumor suppressor (kidney and intestine).^[9]

TMIGD1
Identifiers
Aliases	TMIGD1, TMIGD, UNQ9372, transmembrane and immunoglobulin domain containing 1
External IDs	MGI: 1913851; HomoloGene: 41641; GeneCards: TMIGD1; OMA:TMIGD1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q11.2 Start 30,316,333 bp[1] End 30,334,059 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B5 Start 76,792,985 bp[2] End 76,807,413 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in rectum mucosa of transverse colon epithelium of colon human kidney smooth muscle tissue duodenum appendix renal cortex muscle layer of sigmoid colon lymph node Top expressed in intestinal villus right kidney human kidney ileum Paneth cell proximal tubule jejunum esophagus submandibular gland epithelium of small intestine More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 388364 66601 Ensembl ENSG00000182271 ENSMUSG00000020839 UniProt Q6UXZ0 Q9D7L8 RefSeq (mRNA) NM_206832 NM_001319942 NM_025655 NM_001382246 NM_001382247 RefSeq (protein) NP_001306871 NP_996663 NP_079931 NP_001369175 NP_001369176 Location (UCSC) Chr 17: 30.32 – 30.33 Mb Chr 11: 76.79 – 76.81 Mb PubMed search [3] [4]
Wikidata
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