TMSB10

Thymosin beta-10 is a protein that in humans is encoded by the TMSB10 gene.^[3][4][5] TMSB10 is a member of the beta-thymosin family of peptides.

TMSB10
Identifiers
Aliases	TMSB10, MIG12, TB10, thymosin beta 10
External IDs	OMIM: 188399; GeneCards: TMSB10; OMA:TMSB10 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p11.2 Start 84,905,656 bp[1] End 84,906,671 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte mucosa of transverse colon granulocyte ganglionic eminence stromal cell of endometrium right lung upper lobe of left lung mucosa of sigmoid colon tibial nerve Achilles tendon n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function actin binding protein binding actin monomer binding Cellular component cytoskeleton cytoplasm Biological process actin filament organization regulation of cell migration sequestering of actin monomers Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9168 n/a Ensembl ENSG00000034510 n/a UniProt P63313 n/a RefSeq (mRNA) NM_021103 n/a RefSeq (protein) NP_066926 n/a Location (UCSC) Chr 2: 84.91 – 84.91 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

TMSB10 plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).^{[citation needed]}