TMX3

Protein disulfide-isomerase TMX3 is an enzyme that in humans is encoded by the TMX3 gene.^[4][5]

TMX3
Identifiers
Aliases	TMX3, PDIA13, TXNDC10, thioredoxin related transmembrane protein 3
External IDs	OMIM: 616102; MGI: 2442418; HomoloGene: 10381; GeneCards: TMX3; OMA:TMX3 - orthologs
Gene location (Mouse) Chr. Chromosome 18 (mouse)[1] Band 18|18 E4 Start 90,528,278 bp[1] End 90,561,391 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in otolith organ utricle hand superior cervical ganglion olfactory epithelium endothelial cell of lymphatic vessel supraoptic nucleus Epithelium of choroid plexus substantia nigra dorsomedial hypothalamic nucleus BioGPS More reference expression data
Gene ontology Molecular function protein binding isomerase activity thiol oxidase activity protein disulfide isomerase activity Cellular component integral component of membrane cell surface endoplasmic reticulum membrane endoplasmic reticulum membrane platelet alpha granule membrane plasma membrane Biological process peptidyl-cysteine oxidation protein folding response to endoplasmic reticulum stress cell redox homeostasis platelet degranulation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54495 67988 Ensembl ENSG00000166479 ENSMUSG00000024614 UniProt Q96JJ7 Q8BXZ1 RefSeq (mRNA) NM_019022 NM_198295 RefSeq (protein) NP_061895 NP_001337441 NP_001337442 NP_001337443 NP_001337444 NP_001337445 NP_001337446 NP_938037 Location (UCSC) n/a Chr 18: 90.53 – 90.56 Mb PubMed search [2] [3]
Wikidata
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