TNIP3 (gene)

TNFAIP3 interacting protein 3 is a protein that in humans is encoded by the TNIP3 gene. ^[5]

TNIP3
Identifiers
Aliases	TNIP3, ABIN-3, LIND, TNFAIP3 interacting protein 3
External IDs	OMIM: 608019; MGI: 3041165; HomoloGene: 47979; GeneCards: TNIP3; OMA:TNIP3 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q27 Start 121,131,408 bp[1] End 121,227,466 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 C1 Start 65,502,297 bp[2] End 65,611,024 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad epithelium of colon appendix lymph node gallbladder stromal cell of endometrium upper lobe of left lung prefrontal cortex tonsil Top expressed in secondary oocyte zygote primary oocyte embryo colon white adipose tissue thymus ileum lung heart More reference expression data BioGPS n/a
Gene ontology Molecular function polyubiquitin modification-dependent protein binding protein binding protein kinase binding Cellular component cytosol cytoplasm Biological process inflammatory response toll-like receptor 4 signaling pathway MyD88-independent toll-like receptor signaling pathway negative regulation of I-kappaB kinase/NF-kappaB signaling cellular response to lipopolysaccharide protein deubiquitination positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79931 414084 Ensembl ENSG00000050730 ENSMUSG00000044162 UniProt Q96KP6 n/a RefSeq (mRNA) NM_001128843 NM_001244764 NM_024873 NM_001001495 RefSeq (protein) NP_001122315 NP_001231693 NP_079149 n/a Location (UCSC) Chr 4: 121.13 – 121.23 Mb Chr 6: 65.5 – 65.61 Mb PubMed search [3] [4]
Wikidata
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