TNP1

Spermatid nuclear transition protein 1 is a protein that in humans is encoded by the TNP1 gene.^[5][6]

TNP1
Identifiers
Aliases	TNP1, TP1, transition protein 1
External IDs	OMIM: 190231; MGI: 98784; HomoloGene: 136517; GeneCards: TNP1; OMA:TNP1 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q35 Start 216,859,458 bp[1] End 216,860,064 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 C3|1 36.94 cM Start 73,054,233 bp[2] End 73,055,068 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm right testis left testis testicle cartilage tissue tail of epididymis cerebellar vermis caput epididymis paraflocculus of cerebellum corpus epididymis Top expressed in seminiferous tubule spermatid perirhinal cortex spermatocyte entorhinal cortex interventricular septum cardiac muscle tissue of left ventricle plantaris muscle extensor digitorum longus muscle choroid plexus of fourth ventricle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding Cellular component male germ cell nucleus nucleosome chromosome nucleus Biological process multicellular organism development single strand break repair flagellated sperm motility chromatin remodeling spermatid nucleus differentiation cell differentiation spermatid nucleus elongation nucleosome disassembly negative regulation of transcription, DNA-templated sexual reproduction spermatogenesis spermatid development positive regulation of protein processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7141 21958 Ensembl ENSG00000118245 ENSMUSG00000026182 UniProt P09430 P10856 RefSeq (mRNA) NM_003284 NM_009407 RefSeq (protein) NP_003275 NP_033433 Location (UCSC) Chr 2: 216.86 – 216.86 Mb Chr 1: 73.05 – 73.06 Mb PubMed search [3] [4]
Wikidata
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