TNPO2

Transportin-2 is a protein that in humans is encoded by the TNPO2 gene.^[5][6][7]

TNPO2
Identifiers
Aliases	TNPO2, IPO3, KPNB2B, TRN2, transportin 2
External IDs	OMIM: 603002; MGI: 2384849; HomoloGene: 8381; GeneCards: TNPO2; OMA:TNPO2 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.13 Start 12,699,194 bp[1] End 12,724,011 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 C3 Start 85,763,544 bp[2] End 85,784,212 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in inferior olivary nucleus dorsal motor nucleus of vagus nerve entorhinal cortex lateral nuclear group of thalamus pons Brodmann area 46 nipple ventral tegmental area superior vestibular nucleus orbitofrontal cortex Top expressed in perirhinal cortex entorhinal cortex CA3 field visual cortex Ileal epithelium corneal stroma primary visual cortex superior frontal gyrus dentate gyrus of hippocampal formation granule cell lactiferous gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding nuclear localization sequence binding Cellular component nuclear membrane nuclear periphery nucleus cytoplasm Biological process protein transport intracellular protein transport ribosomal protein import into nucleus NLS-bearing protein import into nucleus protein import into nucleus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 30000 212999 Ensembl ENSG00000105576 ENSMUSG00000031691 UniProt O14787 Q99LG2 RefSeq (mRNA) NM_013433 NM_001136195 NM_001136196 NM_001122843 NM_145390 NM_001364031 NM_001364032 NM_001364033 NM_001364034 NM_001379096 RefSeq (protein) NP_001129667 NP_001129668 NP_038461 NP_001369165 NP_001369166 NP_001369167 NP_001369168 NP_001369169 NP_001369170 NP_001369171 NP_001369172 NP_001129667.1 NP_038461.2 NP_001116315 NP_663365 NP_001350960 NP_001350961 NP_001350962 NP_001350963 NP_001366025 Location (UCSC) Chr 19: 12.7 – 12.72 Mb Chr 8: 85.76 – 85.78 Mb PubMed search [3] [4]
Wikidata
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Interactions

TNPO2 has been shown to interact with NXF1,^[6] NUP98^[8] and Ran (biology).^[6]