TOE1

Target of EGR1 protein 1 is a protein that in humans is encoded by the TOE1 gene.^[5][6]

TOE1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2FC6
Identifiers
Aliases	TOE1, hCaf1z, target of EGR1, member 1 (nuclear), PCH7, target of EGR1, exonuclease, TOE-1
External IDs	OMIM: 613931; MGI: 1915526; HomoloGene: 11823; GeneCards: TOE1; OMA:TOE1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p34.1 Start 45,340,052 bp[1] End 45,343,973 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D1 Start 116,651,507 bp[2] End 116,664,837 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in olfactory bulb gonad parotid gland mucosa of transverse colon right lobe of thyroid gland left testis granulocyte right testis smooth muscle tissue rectum Top expressed in primitive streak renal corpuscle morula blastocyst spermatocyte epiblast superior cervical ganglion medullary collecting duct seminal vesicula ureter More reference expression data BioGPS More reference expression data
Gene ontology Molecular function 3'-5'-exoribonuclease activity protein binding metal ion binding nucleic acid binding poly(A)-specific ribonuclease activity snRNA binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoplasm Cajal body nuclear speck nucleolus nucleoplasm nucleus nuclear body Biological process RNA phosphodiester bond hydrolysis, exonucleolytic snRNA 3'-end processing regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 114034 68276 Ensembl ENSG00000132773 ENSMUSG00000028688 UniProt Q96GM8 Q9D2E2 RefSeq (mRNA) NM_025077 NM_026654 RefSeq (protein) NP_079353 NP_080930 Location (UCSC) Chr 1: 45.34 – 45.34 Mb Chr 4: 116.65 – 116.66 Mb PubMed search [3] [4]
Wikidata
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