TRAK2

Trafficking kinesin-binding protein 2 is a protein that in humans is encoded by the TRAK2 gene.^[5][6][7]

TRAK2
Identifiers
Aliases	TRAK2, ALS2CR3, CALS-C, GRIF-1, GRIF1, MILT2, OIP98, trafficking kinesin protein 2
External IDs	OMIM: 607334; MGI: 1918077; HomoloGene: 22861; GeneCards: TRAK2; OMA:TRAK2 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q33.1 Start 201,377,207 bp[1] End 201,451,500 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C1.3 Start 58,900,449 bp[2] End 58,973,430 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in dorsal motor nucleus of vagus nerve optic nerve trabecular bone tendon of biceps brachii Epithelium of choroid plexus inferior olivary nucleus C1 segment inferior ganglion of vagus nerve right ventricle subthalamic nucleus Top expressed in globus pallidus otolith organ digastric muscle utricle bone marrow soleus muscle vastus lateralis muscle lumbar subsegment of spinal cord superior cervical ganglion temporal muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function signaling receptor binding protein binding GABA receptor binding kinesin binding TPR domain binding enzyme binding myosin binding Cellular component cytoplasm endosome plasma membrane early endosome mitochondrion nucleus dendrite cytoplasm dendrite neuron projection soma axonal growth cone cytoplasmic vesicle axon cytoplasm Biological process regulation of transcription by RNA polymerase II protein targeting protein O-linked glycosylation anterograde dendritic transport of mitochondrion endosome to lysosome transport dendrite morphogenesis negative regulation of axonogenesis dendritic transport of mitochondrion anterograde axonal transport protein localization neurogenesis vesicle transport along microtubule mitochondrion distribution anterograde axonal transport of mitochondrion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 66008 70827 Ensembl ENSG00000115993 ENSMUSG00000026028 UniProt O60296 n/a RefSeq (mRNA) NM_015049 NM_172406 RefSeq (protein) NP_055864 n/a Location (UCSC) Chr 2: 201.38 – 201.45 Mb Chr 1: 58.9 – 58.97 Mb PubMed search [3] [4]
Wikidata
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Interactions

TRAK2 has been shown to interact with Kir2.1^[8] and GABRB2.^[9]