TRAPPC9

Trafficking protein particle complex 9 is a protein that in humans is encoded by the TRAPPC9 gene.^[5]

TRAPPC9
Identifiers
Aliases	TRAPPC9, IBP, IKBKBBP, MRT13, NIBP, TRS120, T1, trafficking protein particle complex 9, trafficking protein particle complex subunit 9
External IDs	OMIM: 611966; MGI: 1923760; HomoloGene: 81931; GeneCards: TRAPPC9; OMA:TRAPPC9 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q24.3 Start 139,727,725 bp[1] End 140,458,579 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 D3 Start 72,461,469 bp[2] End 72,933,053 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh gastrocnemius muscle apex of heart pancreatic ductal cell ganglionic eminence right uterine tube prefrontal cortex anterior pituitary islet of Langerhans tendon of biceps brachii Top expressed in neural layer of retina muscle of thigh dentate gyrus of hippocampal formation granule cell primary visual cortex right kidney spermatocyte cerebellar cortex habenula central gray substance of midbrain seminiferous tubule More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytoplasm cytosol trans-Golgi network Golgi apparatus endoplasmic reticulum Golgi membrane TRAPP complex Biological process cell differentiation COPII vesicle coating positive regulation of NF-kappaB transcription factor activity neuron differentiation cerebral cortex development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83696 76510 Ensembl ENSG00000167632 ENSMUSG00000047921 UniProt Q96Q05 Q3U0M1 RefSeq (mRNA) NM_001160372 NM_031466 NM_001321646 NM_001374682 NM_001374683 NM_001374684 NM_001164641 NM_001164642 NM_001164643 NM_029640 NM_180662 RefSeq (protein) NP_001153844 NP_001308575 NP_113654 NP_001361611 NP_001361612 NP_001361613 NP_001158113 NP_001158115 NP_083916 NP_850993 Location (UCSC) Chr 8: 139.73 – 140.46 Mb Chr 15: 72.46 – 72.93 Mb PubMed search [3] [4]
Wikidata
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Function

This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive mental retardation. Alternatively spliced transcript variants have been described.