TRIM16

Tripartite motif-containing protein 16 is a protein that in humans is encoded by the TRIM16 gene.^[4][5]

TRIM16
Identifiers
Aliases	TRIM16, EBBP, tripartite motif containing 16
External IDs	OMIM: 609505; MGI: 2137356; HomoloGene: 4726; GeneCards: TRIM16; OMA:TRIM16 - orthologs
Gene location (Mouse) Chr. Chromosome 11 (mouse)[1] Band 11|11 B2 Start 62,711,057 bp[1] End 62,741,634 bp[1]
Gene ontology Molecular function DNA binding zinc ion binding interleukin-1 binding protein binding metal ion binding NACHT domain binding transferase activity Cellular component cytoplasm PML body intracellular anatomical structure cytosol plasma membrane Biological process histone H4 acetylation positive regulation of keratinocyte differentiation positive regulation of transcription, DNA-templated response to organophosphorus positive regulation of retinoic acid receptor signaling pathway response to retinoic acid histone H3 acetylation response to growth hormone Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10626 94092 Ensembl ENSG00000221926 ENSMUSG00000047821 UniProt O95361 Q99PP9 RefSeq (mRNA) NM_006470 NM_053169 RefSeq (protein) NP_006461 NP_001335049 NP_001335050 NP_001335051 NP_001335053 NP_001335054 NP_001335055 NP_001335048 NP_444399 Location (UCSC) n/a Chr 11: 62.71 – 62.74 Mb PubMed search [2] [3]
Wikidata
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This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family.

The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined.^[5]