TRIM55

Tripartite motif-containing protein 55 is a protein that in humans is encoded by the TRIM55 gene.^[5][6]

TRIM55
Identifiers
Aliases	TRIM55, MURF-2, RNF29, muRF2, tripartite motif containing 55
External IDs	OMIM: 606469; MGI: 3036269; HomoloGene: 13205; GeneCards: TRIM55; OMA:TRIM55 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q13.1 Start 66,126,896 bp[1] End 66,175,485 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 A2 Start 19,698,638 bp[2] End 19,746,585 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right auricle of heart myocardium of left ventricle cardiac muscle tissue of right atrium apex of heart muscle of thigh deltoid muscle tibialis anterior muscle right lobe of liver gastrocnemius muscle biceps brachii Top expressed in heart skeletal muscle tissue quadriceps femoris muscle muscle of thigh esophagus embryo zone of skin lip lens neural tube More reference expression data BioGPS n/a
Gene ontology Molecular function zinc ion binding protein binding signal transducer activity metal ion binding identical protein binding Cellular component cytoplasm microtubule intracellular anatomical structure nucleus Biological process signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84675 381485 Ensembl ENSG00000147573 ENSMUSG00000060913 UniProt Q9BYV6 G3X8Y1 RefSeq (mRNA) NM_033058 NM_184085 NM_184086 NM_184087 NM_001081281 RefSeq (protein) NP_149047 NP_908973 NP_908974 NP_908975 NP_001074750 Location (UCSC) Chr 8: 66.13 – 66.18 Mb Chr 3: 19.7 – 19.75 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described.^[6]