TRIP11

Thyroid receptor-interacting protein 11 is a protein that in humans is encoded by the TRIP11 gene.^[5][6][7]

TRIP11
Identifiers
Aliases	TRIP11, ACG1A, CEV14, GMAP-210, TRIP-11, TRIP230, GMAP210, thyroid hormone receptor interactor 11, ODCD, ODCD1
External IDs	OMIM: 604505; MGI: 1924393; HomoloGene: 20897; GeneCards: TRIP11; OMA:TRIP11 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q32.12 Start 91,965,991 bp[1] End 92,040,896 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 E Start 101,800,302 bp[2] End 101,879,526 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon testicle buccal mucosa cell epithelium of colon stromal cell of endometrium islet of Langerhans sural nerve gonad body of pancreas monocyte Top expressed in epithelium of small intestine lacrimal gland retinal pigment epithelium substantia nigra parotid gland fossa ciliary body Paneth cell Epithelium of choroid plexus conjunctival fornix More reference expression data BioGPS n/a
Gene ontology Molecular function transcription coactivator activity protein binding Cellular component cytoplasm inner acrosomal membrane Golgi membrane cis-Golgi network Golgi apparatus outer acrosomal membrane cytoskeleton membrane acrosomal membrane nucleus transport vesicle cilium nuclear speck Biological process transcription by RNA polymerase II ventricular septum development bone development inner ear receptor cell stereocilium organization Golgi organization chondrocyte differentiation involved in endochondral bone morphogenesis protein glycosylation intraciliary transport involved in cilium assembly positive regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9321 109181 Ensembl ENSG00000100815 ENSMUSG00000021188 UniProt Q15643 n/a RefSeq (mRNA) NM_004239 NM_001321851 NM_028446 RefSeq (protein) NP_001308780 NP_004230 n/a Location (UCSC) Chr 14: 91.97 – 92.04 Mb Chr 12: 101.8 – 101.88 Mb PubMed search [3] [4]
Wikidata
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Function

TRIP11 was first identified through its ability to interact functionally with thyroid hormone receptor-beta (THRB; MIM 190160). It has also been found in association with the Golgi apparatus and microtubules.[supplied by OMIM]^[7]

Interactions

TRIP11 has been shown to interact with Retinoblastoma protein^[8] and Thyroid hormone receptor alpha.^[8]