TSHB

Thyroid stimulating hormone, beta also known as TSHB is a protein which in humans is encoded by the TSHB gene.^[5][6]

TSHB
Identifiers
Aliases	TSHB, TSH-B, TSH-BETA, thyroid stimulating hormone beta, Thyroid stimulating hormone, beta, thyroid stimulating hormone subunit beta
External IDs	OMIM: 188540; MGI: 98848; HomoloGene: 463; GeneCards: TSHB; OMA:TSHB - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p13.2 Start 115,029,826 bp[1] End 115,034,302 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3 F2.2|3 45.25 cM Start 102,682,781 bp[2] End 102,690,034 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary testicle buccal mucosa cell tibialis anterior muscle tibial arteries gastric mucosa islet of Langerhans Descending thoracic aorta body of uterus Achilles tendon Top expressed in pituitary gland median eminence anterior pituitary arcuate nucleus left lung lobe embryo pars tuberalis granulocyte pars distalis of adenohypophysis ascending aorta More reference expression data BioGPS n/a
Gene ontology Molecular function hormone activity Cellular component extracellular region extracellular space cytoplasm Biological process response to calcium ion cell-cell signaling anatomical structure morphogenesis G protein-coupled receptor signaling pathway response to vitamin A peptide hormone processing response to estrogen hormone-mediated signaling pathway regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7252 22094 Ensembl ENSG00000134200 ENSMUSG00000027857 UniProt P01222 P12656 RefSeq (mRNA) NM_000549 NM_001277991 NM_001165939 NM_001165940 NM_009432 RefSeq (protein) NP_000540 NP_001264920 NP_001159411 NP_001159412 NP_033458 Location (UCSC) Chr 1: 115.03 – 115.03 Mb Chr 3: 102.68 – 102.69 Mb PubMed search [3] [4]
Wikidata
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Function

Thyrotropin-stimulating hormone (TSH) is a noncovalently linked glycoprotein heterodimer and is part of a family of pituitary hormones containing a common alpha subunit (TSHA) and a unique beta subunit (this protein) that confers specificity.^[7]

See also

• thyroid stimulating hormone