TSPAN13

Tetraspanin-13 is a protein that in humans is encoded by the TSPAN13 gene.^[5]

TSPAN13
Identifiers
Aliases	TSPAN13, NET-6, NET6, TM4SF13, tetraspanin 13
External IDs	OMIM: 613139; MGI: 1913359; HomoloGene: 8671; GeneCards: TSPAN13; OMA:TSPAN13 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p21.1 Start 16,753,755 bp[1] End 16,784,536 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 A3 Start 36,064,556 bp[2] End 36,092,499 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in parotid gland visceral pleura jejunal mucosa endothelial cell mucosa of sigmoid colon Brodmann area 23 lower lobe of lung germinal epithelium bronchial epithelial cell middle temporal gyrus Top expressed in habenula lacrimal gland subiculum utricle transitional epithelium of urinary bladder crypt of lieberkuhn of small intestine salivary gland parotid gland olfactory tubercle right lung More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium channel regulator activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process cell surface receptor signaling pathway regulation of calcium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27075 66109 Ensembl ENSG00000106537 ENSMUSG00000020577 UniProt O95857 Q9D8C2 RefSeq (mRNA) NM_014399 NM_025359 RefSeq (protein) NP_055214 NP_079635 Location (UCSC) Chr 7: 16.75 – 16.78 Mb Chr 12: 36.06 – 36.09 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.^[5]