Tobamovirus internal ribosome entry site (IRES)

The Tobamovirus internal ribosome entry site (IRES) is an element that allows cap and end-independent translation of mRNA in the host cell.^[1] The IRES achieves this by mediating the internal initiation of translation by recruiting a ribosomal 43S pre-initiation complex directly to the initiation codon and eliminates the requirement for the eukaryotic initiation factor, eIF4F.^[2]

Tobamovirus internal ribosome entry site (IRES)
Predicted secondary structure and sequence conservation of IRES_Tobamo
Identifiers
Symbol	IRES_Tobamo
Alt. Symbols	Tobamo_IRES
Rfam	RF00225
Other data
RNA type	Cis-reg; IRES
Domain(s)	Viruses
GO	GO:0043022
SO	SO:0000243
PDB structures	PDBe

See also

• Mnt IRES
• N-myc IRES
• TrkB IRES