TrkB IRES

The TrkB internal ribosome entry site (IRES) is an RNA element which is present in the 5' UTR sequence of the mRNA. TrkB is a neurotrophin receptor which is essential for the development and maintenance of the nervous system. The internal ribosome entry site IRES element allows cap-independent translation of TrkB which may be needed for efficient translation in neuronal dendrites.^[1]

TrkB IRES
Predicted secondary structure and sequence conservation of IRES_TrkB
Identifiers
Symbol	IRES_TrkB
Rfam	RF00547
Other data
RNA type	Cis-reg; IRES
Domain(s)	Eukaryota
GO	GO:0043022
SO	SO:0000243
PDB structures	PDBe

See also

• Mnt IRES
• N-myc IRES
• Tobamovirus IRES