Transcription termination factor, RNA polymerase I

Not to be confused with thyroid transcription factor 1.

Transcription termination factor 1 is a protein that in humans is encoded by the TTF1 gene.^[5][6]

TTF1
Identifiers
Aliases	TTF1, TTF-1, TTF-I, Transcription termination factor, RNA polymerase I, transcription termination factor 1
External IDs	OMIM: 600777; MGI: 105044; HomoloGene: 135863; GeneCards: TTF1; OMA:TTF1 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q34.13 Start 132,375,548 bp[1] End 132,406,851 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 A3 Start 28,950,274 bp[2] End 28,977,668 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell trabecular bone oocyte secondary oocyte pylorus pericardium cardia nipple superior surface of tongue vena cava Top expressed in gastrula neural layer of retina submandibular gland spermatocyte granulocyte Paneth cell thymus ventricular zone morula morula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific DNA binding chromatin binding Cellular component plasma membrane nucleolus nucleoplasm cytosol nucleus Biological process DNA-templated transcription, termination negative regulation of DNA replication regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II cell differentiation termination of RNA polymerase I transcription Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7270 22130 Ensembl ENSG00000125482 ENSMUSG00000026803 UniProt Q15361 Q62187 RefSeq (mRNA) NM_001205296 NM_007344 NM_009442 RefSeq (protein) NP_001192225 NP_031370 NP_033468 Location (UCSC) Chr 9: 132.38 – 132.41 Mb Chr 2: 28.95 – 28.98 Mb PubMed search [3] [4]
Wikidata
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