UBAP2

Ubiquitin-associated protein 2 is a protein that in humans is encoded by the UBAP2 gene.^[5][6]

UBAP2
Identifiers
Aliases	UBAP2, UBAP-2, ubiquitin associated protein 2
External IDs	MGI: 1916176; HomoloGene: 73649; GeneCards: UBAP2; OMA:UBAP2 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9p13.3 Start 33,921,693 bp[1] End 34,048,949 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 A5 Start 41,194,313 bp[2] End 41,275,144 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm pancreatic ductal cell vastus lateralis muscle gonad Skeletal muscle tissue of biceps brachii secondary oocyte Achilles tendon Skeletal muscle tissue of rectus abdominis body of tongue sural nerve Top expressed in tail of embryo genital tubercle zygote Ileal epithelium secondary oocyte yolk sac muscle of thigh seminiferous tubule epiblast otic vesicle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA binding cadherin binding Cellular component nucleus cytoplasm Biological process positive regulation of gene expression Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55833 68926 Ensembl ENSG00000137073 ENSMUSG00000028433 UniProt Q5T6F2 Q91VX2 RefSeq (mRNA) NM_020867 NM_001282529 NM_001282530 NM_018449 NM_026872 RefSeq (protein) NP_001269459 NP_060919 NP_001356988 NP_001356991 NP_001356993 NP_001356995 NP_001356996 NP_001356997 NP_081148 Location (UCSC) Chr 9: 33.92 – 34.05 Mb Chr 4: 41.19 – 41.28 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Function

This gene is a novel gene isolated based on its expression in the human adrenal gland. The full-length protein encoded by this gene contains a UBA-domain (ubiquitin associated domain), which is a motif found in several proteins having connections to ubiquitin and the ubiquitination pathway. In addition, the protein contains a region similar to a domain found in members of the atrophin-1 family. The function of this protein has not been determined. Additional alternate splice variants may exist, but their full length nature has not been determined.^[6]