UBR4

E3 ubiquitin-protein ligase UBR4 is an enzyme that in humans is encoded by the UBR4 gene.^[5][6][7][8]

UBR4
Identifiers
Aliases	UBR4, RBAF600, ZUBR1, p600, ubiquitin protein ligase E3 component n-recognin 4
External IDs	OMIM: 609890; MGI: 1916366; HomoloGene: 10804; GeneCards: UBR4; OMA:UBR4 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.13 Start 19,074,510 bp[1] End 19,210,266 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D3 Start 139,079,920 bp[2] End 139,216,899 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of leg skin of abdomen right testis left testis gastric mucosa anterior pituitary stromal cell of endometrium apex of heart right lung left ovary Top expressed in entorhinal cortex perirhinal cortex lactiferous gland CA3 field muscle of thigh neural layer of retina dentate gyrus of hippocampal formation granule cell superior frontal gyrus ventricular zone choroid plexus of fourth ventricle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding protein binding metal ion binding calmodulin binding ubiquitin-protein transferase activity transferase activity Cellular component integral component of membrane centrosome cytoskeleton membrane nucleus nucleoplasm cytoplasm cytosol plasma membrane specific granule membrane tertiary granule membrane ficolin-1-rich granule membrane Biological process viral process protein ubiquitination neutrophil degranulation ubiquitin-dependent protein catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23352 69116 Ensembl ENSG00000127481 ENSMUSG00000066036 UniProt Q5T4S7 A2AN08 RefSeq (mRNA) NM_020765 NM_001160319 RefSeq (protein) NP_065816 NP_001153791 Location (UCSC) Chr 1: 19.07 – 19.21 Mb Chr 4: 139.08 – 139.22 Mb PubMed search [3] [4]
Wikidata
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