USP51

Ubiquitin carboxyl-terminal hydrolase 51 is an enzyme that in humans is encoded by the USP51 gene.^[5][6]

USP51
Identifiers
Aliases	USP51, ubiquitin specific peptidase 51
External IDs	MGI: 3588217; HomoloGene: 71495; GeneCards: USP51; OMA:USP51 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.21 Start 55,484,616 bp[1] End 55,489,848 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X F3 Start 151,789,465 bp[2] End 151,792,412 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis caput epididymis gonad bronchial epithelial cell retinal pigment epithelium tail of epididymis testicle endothelial cell buccal mucosa cell mucosa of paranasal sinus Top expressed in yolk sac secondary oocyte morula zygote embryo primary oocyte embryo epiblast placenta ventricular zone More reference expression data BioGPS n/a
Gene ontology Molecular function thiol-dependent deubiquitinase zinc ion binding peptidase activity cysteine-type peptidase activity hydrolase activity metal ion binding chromatin binding histone binding Cellular component chromosome Biological process protein deubiquitination ubiquitin-dependent protein catabolic process proteolysis histone deubiquitination regulation of response to DNA damage stimulus regulation of cell cycle process regulation of double-strand break repair via homologous recombination regulation of double-strand break repair via nonhomologous end joining DNA repair cellular response to DNA damage stimulus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 158880 635253 Ensembl ENSG00000247746 ENSMUSG00000067215 UniProt Q70EK9 B1AY15 RefSeq (mRNA) NM_201286 NM_001137547 RefSeq (protein) NP_958443 NP_001131019 Location (UCSC) Chr X: 55.48 – 55.49 Mb Chr X: 151.79 – 151.79 Mb PubMed search [3] [4]
Wikidata
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