VPS36

Vacuolar protein-sorting-associated protein 36 is a protein that in humans is encoded by the VPS36 gene.^[5][6][7]

VPS36
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2HTH, 2ZME, 3CUQ
Identifiers
Aliases	VPS36, C13orf9, EAP45, CGI-145, vacuolar protein sorting 36 homolog
External IDs	OMIM: 610903; MGI: 1917410; HomoloGene: 9374; GeneCards: VPS36; OMA:VPS36 - orthologs
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q14.3 Start 52,412,602 bp[1] End 52,450,634 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 A2 Start 22,682,825 bp[2] End 22,710,859 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of arm mucosa of ileum skin of hip skin of thigh pancreatic epithelial cell pancreatic ductal cell tibialis anterior muscle endothelial cell skin of abdomen gingival epithelium Top expressed in trigeminal ganglion urothelium transitional epithelium of urinary bladder Paneth cell hair follicle ureter medullary collecting duct otic vesicle endocardial cushion spermatid More reference expression data BioGPS More reference expression data
Gene ontology Molecular function phosphatidylinositol-3-phosphate binding protein C-terminus binding ubiquitin binding protein binding lipid binding Cellular component cytoplasm cytosol late endosome membrane late endosome membrane lysosome extracellular exosome nucleus endosome ESCRT II complex Biological process regulation of transcription, DNA-templated multivesicular body assembly transcription, DNA-templated endosomal transport protein transport protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway macroautophagy transport endosome transport via multivesicular body sorting pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51028 70160 Ensembl ENSG00000136100 ENSMUSG00000031479 UniProt Q86VN1 Q91XD6 RefSeq (mRNA) NM_016075 NM_001282168 NM_001282169 NM_027338 NM_001368379 RefSeq (protein) NP_001269097 NP_001269098 NP_057159 NP_081614 NP_001355308 Location (UCSC) Chr 13: 52.41 – 52.45 Mb Chr 8: 22.68 – 22.71 Mb PubMed search [3] [4]
Wikidata
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