VTI1B

Vesicle transport through interaction with t-SNAREs homolog 1B is a protein that in humans is encoded by the VTI1B gene.^[5][6][7]

VTI1B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2V8S
Identifiers
Aliases	VTI1B, VTI1, VTI1-LIKE, VTI1L, VTI2, v-SNARE, vti1-rp1, vesicle transport through interaction with t-SNAREs 1B
External IDs	OMIM: 603207; MGI: 1855688; HomoloGene: 38178; GeneCards: VTI1B; OMA:VTI1B - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q24.1 Start 67,647,085 bp[1] End 67,674,820 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 C3 Start 79,202,791 bp[2] End 79,219,441 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in C1 segment amygdala anterior cingulate cortex nucleus accumbens prefrontal cortex right frontal lobe putamen caudate nucleus hypothalamus optic nerve Top expressed in dorsal striatum globus pallidus olfactory tubercle amygdala nucleus accumbens transitional epithelium of urinary bladder cingulate gyrus arcuate nucleus prefrontal cortex paraventricular nucleus of hypothalamus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function SNAP receptor activity protein binding chloride channel inhibitor activity SNARE binding Cellular component integral component of membrane recycling endosome vesicle endosome Golgi apparatus intracellular membrane-bounded organelle late endosome membrane synaptic vesicle membrane lysosomal membrane soma perinuclear region of cytoplasm lysosome ER to Golgi transport vesicle membrane SNARE complex endoplasmic reticulum membrane extracellular region cytosol platelet alpha granule lumen early endosome membrane recycling endosome membrane Biological process membrane fusion vesicle docking involved in exocytosis autophagosome maturation protein transport cell population proliferation intracellular protein transport vesicle-mediated transport regulation of protein localization to plasma membrane Golgi to vacuole transport vesicle fusion with Golgi apparatus endoplasmic reticulum to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport protein targeting to vacuole retrograde transport, endosome to Golgi platelet degranulation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10490 53612 Ensembl ENSG00000100568 ENSMUSG00000021124 UniProt Q9UEU0 O88384 RefSeq (mRNA) NM_006370 NM_016800 NM_001364374 RefSeq (protein) NP_006361 n/a Location (UCSC) Chr 14: 67.65 – 67.67 Mb Chr 12: 79.2 – 79.22 Mb PubMed search [3] [4]
Wikidata
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Interactions

VTI1B has been shown to interact with STX8.^[8][9]