WDR72

WD repeat-containing protein 72 is a protein that in humans is encoded by the WDR72 gene.^[5] WDR72 contains 7 WD40 repeats, which are predicted to form the blades of a 7 beta propeller structure.

WDR72
Identifiers
Aliases	WDR72, AI2A3, WD repeat domain 72
External IDs	OMIM: 613214; MGI: 3583957; HomoloGene: 52326; GeneCards: WDR72; OMA:WDR72 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q21.3 Start 53,513,741 bp[1] End 53,762,878 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 D Start 74,017,638 bp[2] End 74,190,590 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell renal medulla parotid gland thyroid gland liver right lobe of thyroid gland left lobe of thyroid gland right lobe of liver human kidney skin of thigh Top expressed in right kidney human kidney renal cortex proximal tubule secondary oocyte morula zygote blastocyst primary oocyte embryo More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 256764 546144 Ensembl ENSG00000166415 ENSMUSG00000044976 UniProt Q3MJ13 D3YYM4 RefSeq (mRNA) NM_001277176 NM_182758 NM_001033500 NM_177908 RefSeq (protein) NP_001264105 NP_877435 NP_001028672 Location (UCSC) Chr 15: 53.51 – 53.76 Mb Chr 9: 74.02 – 74.19 Mb PubMed search [3] [4]
Wikidata
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Clinical significance

Mutations in this gene cause autosomal-recessive hypomaturation amelogenesis imperfecta.^[6]