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YAF2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

YAF2
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YY1-associated factor 2 is a protein that in humans is encoded by the YAF2 gene.[5][6]

Quick Facts Available structures, PDB ...

The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.[6]

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