ZBTB17

Zinc finger and BTB domain-containing protein 17 is a protein that in humans is encoded by the ZBTB17 gene.^[5]

ZBTB17
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LVR, 2LVT, 2LVU, 2M0D, 2M0E, 2M0F, 2N25, 2N26, 2Q81, 3M52, 4U2M, 4U2N, 5ION
Identifiers
Aliases	ZBTB17, MIZ-1, ZNF151, ZNF60, pHZ-67, zinc finger and BTB domain containing 17
External IDs	OMIM: 604084; MGI: 107410; HomoloGene: 2575; GeneCards: ZBTB17; OMA:ZBTB17 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.13 Start 15,941,869 bp[1] End 15,976,132 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D3 Start 141,171,965 bp[2] End 141,195,241 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve tendon of biceps brachii granulocyte apex of heart right lobe of thyroid gland ganglionic eminence left lobe of thyroid gland upper lobe of left lung spleen ectocervix Top expressed in saccule otic placode otic vesicle ventricular zone plantaris muscle extensor digitorum longus muscle muscle of thigh interventricular septum soleus muscle granulocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding protein binding metal ion binding nucleic acid binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific transcription coactivator binding transcription factor binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus nucleoplasm protein-DNA complex protein-containing complex Biological process positive regulation of transcription, DNA-templated multicellular organism development gastrulation with mouth forming second ectoderm development IRE1-mediated unfolded protein response negative regulation of cell cycle regulation of transcription, DNA-templated transcription, DNA-templated transcription by RNA polymerase II negative regulation of cell population proliferation positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7709 22642 Ensembl ENSG00000116809 ENSMUSG00000006215 UniProt Q13105 Q60821 RefSeq (mRNA) NM_001242884 NM_001287603 NM_001287604 NM_003443 NM_001324137 NM_001324138 NM_009541 NM_001378826 NM_001378827 NM_001378828 RefSeq (protein) NP_001229813 NP_001274532 NP_001274533 NP_001311066 NP_001311067 NP_003434 NP_033567 NP_001365755 NP_001365756 NP_001365757 Location (UCSC) Chr 1: 15.94 – 15.98 Mb Chr 4: 141.17 – 141.2 Mb PubMed search [3] [4]
Wikidata
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Interactions

ZBTB17 has been shown to interact with TOPBP1,^[6] Host cell factor C1^[7] and Myc.^[8][9]