ZDHHC17

Palmitoyltransferase ZDHHC17 is an enzyme that contains a DHHC domain that in humans is encoded by the ZDHHC17 gene.^[5][6][7]

ZDHHC17
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3EU9
Identifiers
Aliases	ZDHHC17, HIP14, HIP3, HYPH, HSPC294, zinc finger DHHC-type containing 17, DHHC-17, zinc finger DHHC-type palmitoyltransferase 17, DHHC17
External IDs	OMIM: 607799; MGI: 2445110; HomoloGene: 56324; GeneCards: ZDHHC17; OMA:ZDHHC17 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q21.2 Start 76,764,103 bp[1] End 76,853,696 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 D1 Start 110,777,641 bp[2] End 110,846,001 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum cerebellar vermis Brodmann area 23 lateral nuclear group of thalamus external globus pallidus pars compacta superior vestibular nucleus pars reticulata subthalamic nucleus pons Top expressed in neural layer of retina gastrula Rostral migratory stream lobe of cerebellum cerebellar vermis ascending aorta nucleus of stria terminalis otolith organ inferior colliculi utricle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein-cysteine S-palmitoyltransferase activity transferase activity magnesium ion transmembrane transporter activity signal transducer activity palmitoyltransferase activity protein binding identical protein binding acyltransferase activity Cellular component integral component of membrane Golgi apparatus intracellular membrane-bounded organelle membrane Golgi membrane Golgi-associated vesicle membrane cytoplasmic vesicle membrane cytoplasmic vesicle presynaptic membrane plasma membrane synapse cell junction cytosol Biological process protein palmitoylation positive regulation of I-kappaB kinase/NF-kappaB signaling lipoprotein transport signal transduction magnesium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23390 320150 Ensembl ENSG00000186908 ENSMUSG00000035798 UniProt Q8IUH5 Q80TN5 RefSeq (mRNA) NM_015336 NM_001359626 NM_172554 NM_001359622 NM_001359624 RefSeq (protein) NP_056151 NP_001346555 NP_766142 NP_001346551 NP_001346553 Location (UCSC) Chr 12: 76.76 – 76.85 Mb Chr 10: 110.78 – 110.85 Mb PubMed search [3] [4]
Wikidata
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Interactions

ZDHHC17 has been shown to interact with Huntingtin.^[8][9]