ZFP91

Zinc finger protein 91 homolog is a protein that in humans is encoded by the ZFP91 gene.^[5][6]

ZFP91
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2M9A
Identifiers
Aliases	ZFP91, DMS-8, DSM-8, PZF, ZFP-91, ZNF757, FKSG11, ZFP91 zinc finger protein, ZFP91 zinc finger protein, atypical E3 ubiquitin ligase, DSM8
External IDs	MGI: 104854; HomoloGene: 43144; GeneCards: ZFP91; OMA:ZFP91 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 58,579,063 bp[1] End 58,621,550 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19 A|19 8.73 cM Start 12,744,384 bp[2] End 12,773,490 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibialis anterior muscle mucosa of ileum myocardium of left ventricle deltoid muscle cardiac muscle tissue of right atrium cerebellar vermis skin of arm sperm quadriceps femoris muscle cartilage tissue Top expressed in ascending aorta aortic valve Rostral migratory stream soleus muscle gastrocnemius muscle tibialis anterior muscle plantaris muscle extensor digitorum longus muscle ankle quadriceps femoris muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding nucleic acid binding ubiquitin-protein transferase activity transferase activity DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus nucleolus Biological process protein K63-linked ubiquitination activation of NF-kappaB-inducing kinase activity protein ubiquitination regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 80829 109910 Ensembl ENSG00000186660 ENSMUSG00000024695 UniProt Q96JP5 Q62511 RefSeq (mRNA) NM_053023 NM_001197051 NM_053009 RefSeq (protein) NP_001183980 NP_444251 NP_443735 Location (UCSC) Chr 11: 58.58 – 58.62 Mb Chr 19: 12.74 – 12.77 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. In addition to the monocistronic transcript originating from this locus, a co-transcribed variant composed of ZFP91 and CNTF sequence has been identified. The monocistronic and co-transcribed variants encode distinct isoforms. The co-transcription of ZFP91 and CNTF has also been observed in mouse.^[6]