ZNF16

Zinc finger protein 16 is a protein that in humans is encoded by the ZNF16 gene.^[3]

ZNF16
Identifiers
Aliases	ZNF16, HZF1, KOX9, zinc finger protein 16
External IDs	OMIM: 601262; HomoloGene: 56008; GeneCards: ZNF16; OMA:ZNF16 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q24.3 Start 144,930,358 bp[1] End 144,950,888 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad testicle oocyte ganglionic eminence gastrocnemius muscle muscle of thigh secondary oocyte ventricular zone skin of leg gingival epithelium n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding protein binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus nucleolus Biological process positive regulation of cell cycle phase transition positive regulation of kinase activity cell cycle negative regulation of apoptotic process regulation of transcription, DNA-templated positive regulation of megakaryocyte differentiation positive regulation of cell division positive regulation of erythrocyte differentiation transcription, DNA-templated positive regulation of cell population proliferation cellular response to sodium dodecyl sulfate cell division regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7564 n/a Ensembl ENSG00000170631 n/a UniProt P17020 n/a RefSeq (mRNA) NM_001029976 NM_006958 n/a RefSeq (protein) NP_001025147 NP_008889 n/a Location (UCSC) Chr 8: 144.93 – 144.95 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

The protein encoded by this gene contains a Cys₂His₂ type of zinc finger, and thus may function as a transcription factor. This gene is located in a region close to ZNF7/KOX4, a gene also encoding a zinc finger protein, on chromosome 8. Two alternatively spliced variants, encoding the same protein, have been identified.^[3]