ZNF281

Zinc finger protein 281 is a protein that in humans is encoded by the ZNF281 gene.^[5][6]

ZNF281
Identifiers
Aliases	ZNF281, ZBP-99, ZNP-99, zinc finger protein 281, ZBP99, GZP1
External IDs	MGI: 3029290; HomoloGene: 8270; GeneCards: ZNF281; OMA:ZNF281 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 200,404,940 bp[1] End 200,410,056 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 E4 Start 136,552,639 bp[2] End 136,557,791 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte endothelial cell cerebellar vermis Brodmann area 23 trabecular bone buccal mucosa cell inferior ganglion of vagus nerve visceral pleura Skeletal muscle tissue of rectus abdominis germinal epithelium Top expressed in olfactory tubercle mandibular prominence ascending aorta maxillary prominence superior cervical ganglion hand aortic valve medial geniculate nucleus lateral septal nucleus substantia nigra More reference expression data BioGPS More reference expression data
Gene ontology Molecular function sequence-specific DNA binding DNA binding transcription corepressor activity DNA-binding transcription factor activity metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific protein binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleoplasm nucleus Biological process cell differentiation regulation of transcription, DNA-templated embryonic body morphogenesis negative regulation of transcription by RNA polymerase II negative regulation of gene expression transcription, DNA-templated stem cell differentiation positive regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23528 226442 Ensembl ENSG00000162702 ENSMUSG00000041483 UniProt Q9Y2X9 Q99LI5 RefSeq (mRNA) NM_012482 NM_001281293 NM_001281294 NM_001160251 NM_177643 RefSeq (protein) NP_001268222 NP_001268223 NP_036614 NP_001153723 NP_808311 Location (UCSC) Chr 1: 200.4 – 200.41 Mb Chr 1: 136.55 – 136.56 Mb PubMed search [3] [4]
Wikidata
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See also

• Zinc finger