ZNF41

Zinc finger protein 41 is a protein that in humans is encoded by the ZNF41 gene.^[3][4]

ZNF41
Identifiers
Aliases	ZNF41, MRX89, zinc finger protein 41
External IDs	OMIM: 314995; HomoloGene: 133263; GeneCards: ZNF41; OMA:ZNF41 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.3 Start 47,445,178 bp[1] End 47,483,222 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of leg gonad gastrocnemius muscle muscle of thigh islet of Langerhans apex of heart rectum ganglionic eminence ventricular zone white blood cell n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding protein binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component intracellular anatomical structure nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7592 n/a Ensembl ENSG00000147124 n/a UniProt P51814 n/a RefSeq (mRNA) NM_007130 NM_153380 NM_001324139 NM_001324140 NM_001324141 NM_001324142 NM_001324143 NM_001324144 NM_001324145 NM_001324147 NM_001324148 NM_001324149 NM_001324150 NM_001324151 NM_001324152 NM_001324153 NM_001324154 NM_001324155 NM_001324156 NM_001324157 n/a RefSeq (protein) NP_001311068 NP_001311069 NP_001311070 NP_001311071 NP_001311072 NP_001311073 NP_001311074 NP_001311076 NP_001311077 NP_001311078 NP_001311079 NP_001311080 NP_001311081 NP_001311082 NP_001311083 NP_001311084 NP_001311085 NP_001311086 NP_009061 NP_700359 n/a Location (UCSC) Chr X: 47.45 – 47.48 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

This gene product is a likely zinc finger family transcription factor. It contains KRAB-A and KRAB-B domains that act as transcriptional repressors in related proteins, and multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. This gene is part of a gene cluster on chromosome Xp11.23. Several alternatively spliced transcript variants have been described, however, the full-length nature of only some of them is known.^[4]