ZNF644

Zing finger protein 644 (ZNF644) also known as zinc finger motif enhancer-binding protein 2 (Zep-2) is a protein that in humans is encoded by the ZNF644 gene.^[5]

ZNF644
Identifiers
Aliases	ZNF644, BM-005, MYP21, NatF, ZEP-2, zinc finger protein 644
External IDs	OMIM: 614159; MGI: 1277212; HomoloGene: 12971; GeneCards: ZNF644; OMA:ZNF644 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p22.2 Start 90,915,298 bp[1] End 91,022,272 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5 E5|5 51.43 cM Start 106,616,739 bp[2] End 106,697,287 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon ventricular zone ganglionic eminence tibialis anterior muscle mucosa of ileum testicle epithelium of colon gonad corpus callosum bone marrow cell Top expressed in genital tubercle tail of embryo Gonadal ridge spermatocyte spermatid medial ganglionic eminence extensor digitorum longus muscle cardiac muscle tissue of left ventricle maxillary prominence lobe of cerebellum More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity Cellular component nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84146 52397 Ensembl ENSG00000122482 ENSMUSG00000049606 UniProt Q9H582 n/a RefSeq (mRNA) NM_016620 NM_032186 NM_201269 NM_026856 NM_001363318 NM_001363319 NM_001363320 NM_001363321 NM_001363322 NM_001363323 RefSeq (protein) NP_057704 NP_115562 NP_958357 n/a Location (UCSC) Chr 1: 90.92 – 91.02 Mb Chr 5: 106.62 – 106.7 Mb PubMed search [3] [4]
Wikidata
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Clinical relevance

Mutations in the ZNF644 gene have been found in sporadic cases of high myopia.^[6]