ZNF74

Zinc finger protein 74 is a protein that in humans is encoded by the ZNF74 gene.^[3][4][5] Schizophrenia susceptibility has been associated with a mutation in this protein.^[6]

ZNF74
Identifiers
Aliases	ZNF74, COS52, ZFP520, ZNF520, hZNF7, zinc finger protein 74
External IDs	OMIM: 194548; HomoloGene: 88675; GeneCards: ZNF74; OMA:ZNF74 - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q11.21 Start 20,394,115 bp[1] End 20,408,461 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence gonad ventricular zone buccal mucosa cell stromal cell of endometrium granulocyte prefrontal cortex right hemisphere of cerebellum right frontal lobe anterior cingulate cortex n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity nucleic acid binding DNA binding metal ion binding RNA binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component intracellular anatomical structure nucleus nucleoplasm actin cytoskeleton Biological process multicellular organism development transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7625 n/a Ensembl ENSG00000185252 n/a UniProt Q16587 n/a RefSeq (mRNA) NM_001256523 NM_001256524 NM_001256525 NM_003426 n/a RefSeq (protein) NP_001243452 NP_001243453 NP_001243454 NP_003417 n/a Location (UCSC) Chr 22: 20.39 – 20.41 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Interactions

ZNF74 has been shown to interact with POLR2A.^[7]