2C-CPE

2C-CPE is a designer drug from the substituted phenethylamine family, which was first synthesised by Josh Hartsel and colleagues in 2024. It is a moderately potent agonist at the serotonin receptor 5-HT_2A in vitro, with a binding affinity (K_i) of 134 nM, slightly weaker than the related cyclopropyl compound 2C-CP. It is not known to have been tested in humans or animals.^[1]

2C-CPE

Identifiers
IUPAC name 2-(4-cyclopentyl-2,5-dimethoxyphenyl)ethanamine
PubChem CID	169149436
Chemical and physical data
Formula	C15H23NO2
Molar mass	249.354 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC(=C(C=C1CCN)OC)C2CCCC2
InChI InChI=1S/C15H23NO2/c1-17-14-10-13(11-5-3-4-6-11)15(18-2)9-12(14)7-8-16/h9-11H,3-8,16H2,1-2H3 Key:GIYHLPFOZWFVHO-UHFFFAOYSA-N

See also

• 2C-P
• 2C-Bu
• 2C-iBu