2C-Bu

2C-Bu, also known as 2,5-dimethoxy-4-butylphenethylamine, is a chemical compound of the phenethylamine and 2C families.^[1] It has been said by Daniel Trachsel to be completely unknown.^[1] 2C-Bu is the 2C analogue of the DOx derivative DOBU, which is active but does not appear to have psychedelic-type effects in either animals or humans.^[1][2][3]

2C-Bu

Clinical data
Other names	2,5-Dimethoxy-4-butylphenethylamine; 4-Butyl-2,5-dimethoxyphenethylamine; 2C-BU
Identifiers
IUPAC name 2-(4-butyl-2,5-dimethoxyphenyl)ethan-1-amine
CAS Number	2888537-44-6
PubChem CID	172187929
Chemical and physical data
Formula	C14H23NO2
Molar mass	237.343 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCCC1=CC(=C(C=C1OC)CCN)OC
InChI InChI=1S/C14H23NO2/c1-4-5-6-11-9-14(17-3)12(7-8-15)10-13(11)16-2/h9-10H,4-8,15H2,1-3H3 Key:WVGDKSDIKCPRKV-UHFFFAOYSA-N

2C-Bu has several notable skeletal isomers, including 2C-iBu, 2C-tBu, and 2C-sBu.^[1][4] 2C-iBu and 2C-tBu are both active and produce hallucinogen-type effects in animals and/or humans.^[5][6][7][4] This is in spite of 2C-tBu being predicted to be inactive^[4] and DOTB (the DOx analogue of 2C-tBu) being inactive as a hallucinogen in animals and humans.^[2][8] 2C-iBu may have reduced hallucinogenic potency than other 2C drugs and is being developed as a potential anti-inflammatory medication.^[6][7]

See also

• 2C-P