3C-P

3C-P, also known as 4-propoxy-3,5-dimethoxyamphetamine or as α-methylproscaline (3C-proscaline), is a psychedelic drug of the phenethylamine, amphetamine, and 3C families related to 3,4,5-trimethoxyamphetamine (TMA).^[2][3] It is the amphetamine (3C) analogue of proscaline.^[2][3] The drug has been reported to have a dose range of 20 to 40 mg orally, with a typical dose estimate of 30 mg, based on informal anecdotal reports.^[1] Although 3C-P produces hallucinogenic effects, very little is known about its effects.^[4] The chemical synthesis of 3C-P has been described.^[5] 3C-P acts as a serotonin 5-HT₂ receptor agonist, including of the serotonin 5-HT_2A receptor.^[3][6] It produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents.^[4][1][6] 3C-P was first described in the scientific literature by Otakar Leminger by 1972.^[7][8] Alexander Shulgin mentioned it in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved)^[2] and Daniel Trachsel synthesized it in 2002 but neither reported its effects or properties.^[5][9][10] The drug has been sold online as a designer drug and was first detected in September 2013 in Finland.^[11][12]

3C-P

Clinical data
Other names	4-Propoxy-3,5-dimethoxyamphetamine; 3,5-Dimethoxy-4-propoxyamphetamine; α-Methylproscaline; 3C-Proscaline
Routes of administration	Oral[1]
Drug class	Serotonergic psychedelic; Hallucinogen
Legal status
Legal status	DE: NpSG (Industrial and scientific use only) UK: Class A
Identifiers
IUPAC name 1-(3,5-dimethoxy-4-propoxyphenyl)propan-2-amine
CAS Number	501700-11-4 Y
PubChem CID	54929142
ChemSpider	21106238 Y
UNII	4KRX4MHV7L
CompTox Dashboard (EPA)	DTXSID201234925
Chemical and physical data
Formula	C14H23NO3
Molar mass	253.342 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(N)Cc1cc(OC)c(OCCC)c(c1)OC
InChI InChI=1S/C14H23NO3/c1-5-6-18-14-12(16-3)8-11(7-10(2)15)9-13(14)17-4/h8-10H,5-7,15H2,1-4H3 Y Key:KKMCHCCXGKYEKJ-UHFFFAOYSA-N Y
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See also

• 3C (psychedelics)
• 3C-AL
• 3C-MAL