Proscaline

Proscaline (4-propoxy-3,5-dimethoxyphenethylamine or 4-propoxy-3,5-DMPEA) is a psychedelic and hallucinogenic drug. It has structural properties similar to the drugs mescaline, isoproscaline, and escaline. In PiHKAL, Alexander Shulgin reports that a dose of 30–60 mg produces effects lasting 8–12 hours.^[1][2]

Proscaline

Names
Preferred IUPAC name 2-(3,5-Dimethoxy-4-propoxyphenyl)ethan-1-amine
Identifiers
CAS Number	39201-78-0 Y[EPA]
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL340765 Y
ChemSpider	10439596 Y
PubChem CID	15102790
UNII	99G781N5IO Y
CompTox Dashboard (EPA)	DTXSID00192454
InChI InChI=1S/C13H21NO3/c1-4-7-17-13-11(15-2)8-10(5-6-14)9-12(13)16-3/h8-9H,4-7,14H2,1-3H3 Y Key: HYWLMSUAZVDUFW-UHFFFAOYSA-N Y InChI=1/C13H21NO3/c1-4-7-17-13-11(15-2)8-10(5-6-14)9-12(13)16-3/h8-9H,4-7,14H2,1-3H3 Key: HYWLMSUAZVDUFW-UHFFFAOYAZ
SMILES COc1cc(cc(OC)c1OCCC)CCN
Properties
Chemical formula	C13H21NO3
Molar mass	239.315 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Pharmacology

Proscaline is a serotonin 5-HT₂ receptor agonist.^[3] This is thought to be responsible for its psychedelic effects.^[3]

Chemistry

Proscaline is in a class of compounds commonly known as phenethylamines, and is the 4-propoxy homolog of mescaline. The full name of the chemical is 4-propoxy-3,5-dimethoxyphenethylamine.

Legality

United Kingdom

Proscaline is a Class A controlled substance in the UK.

United States

Proscaline is not directly scheduled under the Controlled Substances Act. However, due to its structural similarities with mescaline, a Schedule I drug, it could potentially be subject to the same control measures and penalties for possession and manufacture under the Federal Analogue Act.

See also

• Substituted mescaline analogue
• Allylescaline
• 3C-P
• Mescaline
• PiHKAL