AHCYL1

Putative adenosylhomocysteinase 2 is an enzyme that in humans is encoded by the AHCYL1 gene.^[5][6][7][8]

AHCYL1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3MTG
Identifiers
Aliases	AHCYL1, DCAL, IRBIT, PPP1R78, PRO0233, XPVKONA, adenosylhomocysteinase like 1
External IDs	OMIM: 607826; MGI: 2385184; HomoloGene: 77353; GeneCards: AHCYL1; OMA:AHCYL1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p13.3 Start 109,984,765 bp[1] End 110,023,742 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3 F2.3|3 46.83 cM Start 107,570,434 bp[2] End 107,603,876 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in external globus pallidus ventral tegmental area superior vestibular nucleus dorsal motor nucleus of vagus nerve pars reticulata internal globus pallidus subthalamic nucleus pars compacta inferior olivary nucleus inferior ganglion of vagus nerve Top expressed in central gray substance of midbrain CA3 field perirhinal cortex anterior horn of spinal cord entorhinal cortex superior colliculus neural layer of retina nucleus of stria terminalis medulla oblongata inferior colliculi More reference expression data BioGPS More reference expression data
Gene ontology Molecular function adenosylhomocysteinase activity protein binding RNA binding identical protein binding Cellular component intracellular membrane-bounded organelle cytosol extracellular exosome membrane endoplasmic reticulum plasma membrane cytoplasm endoplasmic reticulum membrane apical plasma membrane Biological process protein export from nucleus regulation of ion transmembrane transporter activity regulation of anion transport S-adenosylmethionine cycle response to calcium ion mRNA polyadenylation one-carbon metabolic process regulation of cardiac conduction positive regulation of sodium ion transport epithelial fluid transport regulation of mRNA 3'-end processing angiotensin-activated signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10768 229709 Ensembl ENSG00000168710 ENSMUSG00000027893 UniProt O43865 Q80SW1 RefSeq (mRNA) NM_001242673 NM_001242674 NM_001242675 NM_001242676 NM_006621 NM_145542 NM_001357110 NM_001357111 NM_001357112 NM_001357113 RefSeq (protein) NP_001229602 NP_001229603 NP_001229604 NP_001229605 NP_006612 NP_663517 NP_001344039 NP_001344040 NP_001344041 NP_001344042 Location (UCSC) Chr 1: 109.98 – 110.02 Mb Chr 3: 107.57 – 107.6 Mb PubMed search [3] [4]
Wikidata
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Interactions

AHCYL1 has been shown to interact with ITPR1.^[7]