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BRD8

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

BRD8
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Bromodomain-containing protein 8 is a protein that in humans is encoded by the BRD8 gene.[5][6][7]

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The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.[7]

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Interactions

BRD8 has been shown to interact with Thyroid hormone receptor beta[6] and Retinoid X receptor alpha.[8]

References

Further reading

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