CCT4

T-complex protein 1 subunit delta is a protein that in humans is encoded by the CCT4 gene.^[5][6] The CCT4 protein is a component of the TRiC complex.

CCT4
Identifiers
Aliases	CCT4, CCT-DELTA, Cctd, SRB, chaperonin containing TCP1 subunit 4
External IDs	OMIM: 605142; MGI: 104689; HomoloGene: 4695; GeneCards: CCT4; OMA:CCT4 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p15 Start 61,868,085 bp[1] End 61,888,671 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 A3.2|11 14.25 cM Start 22,940,519 bp[2] End 22,953,780 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad ventricular zone parotid gland embryo ganglionic eminence cartilage tissue lactiferous duct epithelium of nasopharynx vulva tibialis anterior muscle Top expressed in Gonadal ridge abdominal wall primitive streak vas deferens medial ganglionic eminence dermis somite migratory enteric neural crest cell Paneth cell mandibular prominence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding protein binding ATP binding protein folding chaperone activity unfolded protein binding RNA binding Cellular component cell body centrosome cell projection melanosome nucleoplasm microtubule organizing center zona pellucida receptor complex chaperonin-containing T-complex microtubule extracellular exosome cytoskeleton cytoplasm cytosol Biological process positive regulation of protein localization to Cajal body positive regulation of establishment of protein localization to telomere scaRNA localization to Cajal body protein stabilization positive regulation of telomere maintenance via telomerase toxin transport protein folding positive regulation of telomerase activity positive regulation of telomerase RNA localization to Cajal body binding of sperm to zona pellucida 'de novo' protein folding chaperone-mediated protein folding Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10575 12464 Ensembl ENSG00000115484 ENSMUSG00000007739 UniProt P50991 P80315 RefSeq (mRNA) NM_006430 NM_001256721 NM_009837 RefSeq (protein) NP_001243650 NP_006421 NP_033967 Location (UCSC) Chr 2: 61.87 – 61.89 Mb Chr 11: 22.94 – 22.95 Mb PubMed search [3] [4]
Wikidata
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Interactions

CCT4 has been shown to interact with PPP4C.^[7][8]