CCT8

T-complex protein 1 subunit theta is a protein that in humans is encoded by the CCT8 gene.^[5][6] The CCT8 protein is a component of the TRiC complex.

CCT8
Identifiers
Aliases	CCT8, C21orf112, Cctq, D21S246, PRED71, chaperonin containing TCP1 subunit 8
External IDs	OMIM: 617786; MGI: 107183; HomoloGene: 4802; GeneCards: CCT8; OMA:CCT8 - orthologs
Gene location (Human) Chr. Chromosome 21 (human)[1] Band 21q21.3 Start 29,055,805 bp[1] End 29,073,797 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 C3.3 Start 87,280,214 bp[2] End 87,292,761 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte gonad secondary oocyte epithelium of nasopharynx embryo ganglionic eminence endothelial cell germinal epithelium Epithelium of choroid plexus ventricular zone Top expressed in otic placode otic vesicle epiblast mandibular prominence maxillary prominence saccule somite primitive streak abdominal wall tail of embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding protein binding ATP binding protein folding chaperone activity unfolded protein binding cadherin binding Cellular component cell body cytosol centrosome cell projection cilium nucleoplasm microtubule organizing center zona pellucida receptor complex intermediate filament cytoskeleton microtubule extracellular exosome cytoskeleton cytoplasm chaperonin-containing T-complex extracellular region secretory granule lumen azurophil granule lumen ficolin-1-rich granule lumen Biological process positive regulation of protein localization to Cajal body positive regulation of establishment of protein localization to telomere pore complex assembly protein stabilization positive regulation of telomere maintenance via telomerase toxin transport positive regulation of telomerase RNA localization to Cajal body binding of sperm to zona pellucida protein folding 'de novo' protein folding neutrophil degranulation chaperone-mediated protein folding Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10694 12469 Ensembl ENSG00000156261 ENSMUSG00000025613 UniProt P50990 P42932 RefSeq (mRNA) NM_006585 NM_001282907 NM_001282908 NM_001282909 NM_009840 RefSeq (protein) NP_001269836 NP_001269837 NP_001269838 NP_006576 NP_033970 Location (UCSC) Chr 21: 29.06 – 29.07 Mb Chr 16: 87.28 – 87.29 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• TCP1, T-complex protein 1 subunit alpha
• Chaperonin