CRYZL1

Quinone oxidoreductase-like protein 1 is an enzyme that in humans is encoded by the CRYZL1 gene.^[5][6]

CRYZL1
Identifiers
Aliases	CRYZL1, 4P11, QOH-1, crystallin zeta like 1
External IDs	OMIM: 603920; MGI: 1913859; HomoloGene: 3749; GeneCards: CRYZL1; OMA:CRYZL1 - orthologs
Gene location (Human) Chr. Chromosome 21 (human)[1] Band 21q22.11 Start 33,589,341 bp[1] End 33,643,926 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 C4 Start 91,486,210 bp[2] End 91,525,863 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence gastric mucosa popliteal artery tibial arteries muscle layer of sigmoid colon ventricular zone Descending thoracic aorta anterior cingulate cortex left ovary amygdala Top expressed in sciatic nerve dentate gyrus of hippocampal formation granule cell Region I of hippocampus proper superior frontal gyrus medial ganglionic eminence cerebellar cortex renal corpuscle primary visual cortex Paneth cell epithelium of lens More reference expression data BioGPS More reference expression data
Gene ontology Molecular function oxidoreductase activity NADP binding NADPH:quinone reductase activity Cellular component cytosol Biological process quinone metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9946 66609 Ensembl ENSG00000205758 ENSMUSG00000058240 UniProt O95825 Q921W4 RefSeq (mRNA) NM_145858 NM_145311 NM_026994 NM_133679 RefSeq (protein) NP_665857 NP_081270 NP_598440 Location (UCSC) Chr 21: 33.59 – 33.64 Mb Chr 16: 91.49 – 91.53 Mb PubMed search [3] [4]
Wikidata
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This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined.^[6]