CYP4X1

CYP4X1 (cytochrome P450, family 4, subfamily X, polypeptide 1) is a protein which in humans is encoded by the CYP4X1 gene.^[5]

CYP4X1
Identifiers
Aliases	CYP4X1, CYPIVX1, cytochrome P450 family 4 subfamily X member 1
External IDs	OMIM: 614999; MGI: 1932403; HomoloGene: 75853; GeneCards: CYP4X1; OMA:CYP4X1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p33|1 Start 47,023,669 bp[1] End 47,050,751 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D1 Start 114,963,520 bp[2] End 114,991,478 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in palpebral conjunctiva trachea bronchial epithelial cell nasal epithelium epithelium of nasopharynx Brodmann area 23 Descending thoracic aorta urethra olfactory zone of nasal mucosa mucosa of paranasal sinus Top expressed in facial motor nucleus lumbar spinal ganglion substantia nigra trigeminal ganglion piriform cortex dorsomedial hypothalamic nucleus medial dorsal nucleus anterior horn of spinal cord medial geniculate nucleus temporal lobe More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 260293 81906 Ensembl ENSG00000186377 ENSMUSG00000047155 UniProt Q8N118 Q6A152 RefSeq (mRNA) NM_178033 NM_001320289 NM_001320290 NM_001003947 RefSeq (protein) NP_001307218 NP_001307219 NP_828847 NP_001003947 Location (UCSC) Chr 1: 47.02 – 47.05 Mb Chr 4: 114.96 – 114.99 Mb PubMed search [3] [4]
Wikidata
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain.^[6]