Daf-4

The DAF-4 gene encodes for the only type II receptor of TGF-beta signaling pathway in the worm Caenorhabditis elegans,^[1] with the ligands Daf-7 or Dbl-1.^[2] When binds to the ligand Daf-7, Daf-4 complexed with the type I receptor Daf-1, and activated the Smad Protein Daf-8/14. By contrast, when binds to Dbl-1, Daf-4 complexed with the Sma-6 type I receptor, and activated the Sma-2/3/4.^[3]

abnormal dauer formation protein 4
Identifiers
Organism	Caenorhabditis elegans
Symbol	daf-4
Entrez	175781
HomoloGene	124563
UniProt	P50488
Other data
Chromosome	III: 5.63 - 5.63 Mb
Search for Structures Swiss-model Domains InterPro