EIF3EIP

Eukaryotic translation initiation factor 3 subunit L (eIF3l), less commonly known as EIF3EIP, is a protein that in humans is encoded by the EIF3L gene.^[5][6][7]

EIF3L
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3J8B, 3J8C
Identifiers
Aliases	EIF3L, EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025, MSTP005, eukaryotic translation initiation factor 3 subunit L
External IDs	MGI: 2386251; HomoloGene: 9380; GeneCards: EIF3L; OMA:EIF3L - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.1 Start 37,848,868 bp[1] End 37,889,407 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15 E1|15 37.7 cM Start 78,959,379 bp[2] End 78,978,605 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad ganglionic eminence ventricular zone left ovary right ovary epithelium of colon stromal cell of endometrium body of pancreas canal of the cervix granulocyte Top expressed in otic vesicle maxillary prominence mandibular prominence primitive streak otic placode abdominal wall somite dermis endocardial cushion vas deferens More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding translation initiation factor activity RNA binding Cellular component nucleolus membrane fibrillar center cytosol nucleoplasm cytoplasm eukaryotic translation initiation factor 3 complex eukaryotic 43S preinitiation complex eukaryotic 48S preinitiation complex Biological process translational initiation viral translational termination-reinitiation protein biosynthesis formation of cytoplasmic translation initiation complex cytoplasmic translational initiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51386 223691 Ensembl ENSG00000100129 ENSMUSG00000033047 UniProt Q9Y262 Q8QZY1 RefSeq (mRNA) NM_001242923 NM_016091 NM_001363785 NM_145139 RefSeq (protein) NP_001229852 NP_057175 NP_001350714 NP_660121 Location (UCSC) Chr 22: 37.85 – 37.89 Mb Chr 15: 78.96 – 78.98 Mb PubMed search [3] [4]
Wikidata
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Interactions

eIF3l has been shown to interact with eIF3a.^[6][8]

See also

• Eukaryotic initiation factor 3 (eIF3)