EIF3H

Eukaryotic translation initiation factor 3 subunit H (eIF3h) is a protein that in humans is encoded by the EIF3H gene.^[5][6]

EIF3H
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3J8B, 3J8C
Identifiers
Aliases	EIF3H, EIF3S3, eIF3-gamma, eIF3-p40, eukaryotic translation initiation factor 3 subunit H
External IDs	OMIM: 603912; MGI: 1915385; HomoloGene: 2785; GeneCards: EIF3H; OMA:EIF3H - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q23.3-q24.11 Start 116,642,130 bp[1] End 116,766,925 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 C Start 51,649,954 bp[2] End 51,728,919 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence gonad left ovary parotid gland monocyte right ovary body of uterus canal of the cervix lymph node ectocervix Top expressed in neural layer of retina yolk sac ventricular zone tail of embryo genital tubercle lip morula dentate gyrus of hippocampal formation granule cell embryo muscle of thigh More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding translation initiation factor activity RNA binding metallopeptidase activity Cellular component cytoplasm cytosol eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex, eIF3m extracellular exosome membrane eukaryotic 43S preinitiation complex eukaryotic 48S preinitiation complex polysomal ribosome Biological process translational initiation regulation of translational initiation protein biosynthesis formation of cytoplasmic translation initiation complex cytoplasmic translational initiation proteolysis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8667 68135 Ensembl ENSG00000147677 ENSMUSG00000022312 UniProt O15372 Q91WK2 RefSeq (mRNA) NM_003756 NM_080635 RefSeq (protein) NP_003747 NP_542366 Location (UCSC) Chr 8: 116.64 – 116.77 Mb Chr 15: 51.65 – 51.73 Mb PubMed search [3] [4]
Wikidata
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Interactions

eIF3h has been shown to interact with eIF3a.^[7][8][9]

See also

• Eukaryotic initiation factor 3 (eIF3)